What is the recommended ratio of medium-chain triglycerides (MCT) in nutritional supplementation for cholestasis?

The recommended ratio of medium-chain triglycerides (MCT) in nutritional supplementation for cholestasis is 1:1. Medium-chain triglycerides are beneficial in the context of cholestasis because they are absorbed more rapidly than long-chain triglycerides and do not require bile for absorption. This makes them particularly useful in patients where bile salt production is impaired, as is the case in cholestasis.

The 1:1 ratio ensures that there is a sufficient quantity of MCT to facilitate adequate energy provision while also allowing for a balanced intake of other nutrients. This ratio supports the nutritional needs of patients, helping to prevent malnutrition, which is a common issue in those with cholestatic liver disease.

In this particular context, the other ratios would not provide the optimal balance necessary for effective supplementation, potentially leading to inadequate caloric intake or inefficient nutrient absorption.