What action should be taken if triglyceride levels exceed 400?

When triglyceride levels exceed 400 mg/dL, it is important to take appropriate action to reduce the risk of pancreatitis, which can occur at high levels of triglycerides. The recommended approach in this scenario is to stop the current lipid-regulating medication, recheck the triglyceride levels, and then, once they are confirmed to be below 400 mg/dL, restart the medication at a lower dosage of 0.5 g/kg/day.

This strategy is grounded in the understanding that persistently high triglyceride levels can pose significant health risks, and thus, it is advisable to reassess and adjust treatment. Restarting at a lower dose after ensuring levels are manageable can help to mitigate potential side effects while still addressing the lipid concerns. This careful management supports patient safety and promotes effective treatment outcomes.